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Wednesday, May 15, 2013

Did you know...

Did you know glucocorticoids, molecules that serve a variety of functions in the body, can influence reward-based reinforcement and memory processing? In vol. 34 no. 1 of Zoological Research, an article, "Blockage of glucocorticoid receptors during memory acquisition, retrieval and reconsolidation prevents the expression of morphineinduced conditioned place preferences in mice" by Fan et al. discusses how the blockage of glucocorticoid receptors during memory functions prevents reward-based reinforcement in mice. In this study, mice were treated with a glucocorticoid antagonist (which blocks the glucocorticoid receptor) and were found to have impaired reward-based memory and sensitization behavior.
For this article and others from this issue, go to: http://www.bioline.org.br/titles?id=zr&year=2013&vol=34&num=01&keys=V34N1

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